Magnetic Levitation

Levitate your cells to 3D!

 

  • Biocompatible nanoparticles to magnetize cells
  • 3D cultures mimicking native tissue environments
  • Magnetized spheroids that are easy to handle/retrieve
  • No special equipment or media needed
Magnetic LevitationMagnetic Levitation

In magnetic levitation, cells are magnetized with NanoShuttleTM-PL through overnight incubation and dispensed into a cell-repellent multiwell plate, where they are levitated off the bottom by a magnet above the plate.1 In levitating cells off the bottom of a multiwell plate, the magnetic forces work as an invisible scaffold that rapidly aggregates cells, and induces cell-cell interactions and ECM synthesis. The 3D culture is formed without any artificial substrate or specialized media or equipment and can be cultured long-term.2 Additionally, adding and removing solutions is made easy by the use of magnets to hold down 3D cultures when removing solutions, limiting culture loss. 3D cultures can also be picked up and transferred between vessels using magnetic tools such as the MagPenTM.

Magnetic levitation is an easy tool to recreate native tissue environments in vitro!

Products

Product Includes Part # Manual Click to Buy!
Single Well Bio-Assembler Kit
  • 600-μL Vials of NanoShuttleTM-PL (2)
  • Single-Well Levitating Drives (3)
  • Single-Well Concentrating Drives (3)
  • Cell-Repellent 35-mm Petri Dishes (10)
  • Holding lid (1)
004-SWK Single Well Bio-Assembler $500
6-well Bio-Assembler Kit
  • 600-μL Vials of NanoShuttleTM-PL (2)
  • 6-Well Levitating Drive (1)
  • 6-Well Concentrating Drive (1)
  • Cell-Repellent 6-Well Plates (2)
007-6WK 6-well Bio-Assembler $500
24-well Bio-Assembler Kit
  • 600-μL Vials of NanoShuttleTM-PL (2)
  • 24-Well Levitating Drive (1)
  • 24-Well Concentrating Drive (1)
  • Cell-Repellent 24-Well Plates (2)
  • Custom lid (1)
009-24WK 24-well Bio-Assembler $750

*US prices only. Ask your local distributor for prices in your region.
Contact us for additional parts.

References

1. Souza, G. R. et al. Three-dimensional tissue culture based on magnetic cell levitation. Nat. Nanotechnol. 5, 291–6 (2010).
2. Daquinag, A. C., Souza, G. R. & Kolonin, M. G. Adipose tissue engineering in three-dimensional levitation tissue culture system based on magnetic nanoparticles. Tissue Eng. Part C. Methods 19, 336–44 (2013).