|
3D Cell Culturing with the Bio-AssemblerTM
One of the greatest obstacles in basic life science research, drug discovery, and regenerative medicine is the lack of an in vitro or test-tube cell-culturing platform that mimics the natural or in vivo environment. The most commonly employed method today for culturing cells is on 2-dimensional (2D) surfaces such as petri-dishes. Although 2D cell culturing has notably improved our understanding of basic cell biology, it is widely recognized that 2D techniques have many limitations when it comes to growing tissue.
The emerging understanding today is that cells that make up tissue in the body have a very complex 3-dimensional architecture and microenvironments that require cells to interact with neighbors more naturally to enable normal cell growth and function. Many 3D cell-culturing technologies are being developed to simulate this complex architecture however these solutions remain slow, complex, lack high throughput, contain non-human biological factors that can preclude therapeutic use, and do not offer the ability to temporally or spatially control the cells. Using a proprietary combination of reagents that are added to media to magnetize cells, n3D created a simple device that can levitate and even manipulate cell cultures. n3D’s "Bio-Assembler™" succeeds in offering an in vivo environment where tissues can grow significantly faster than in any other method currently available in the marketplace. Proof of principal collaborators who tested n3D’s Bio-Assembler™ noted several major advantages over Matrigel™, considered the gold standard in 3D cell culturing today.
n3D is positioned to offer a breakthrough technology to basic life science researchers that could dramatically impact ongoing research at cancer and stem cell laboratories, universities, and biotechnology companies worldwide. Additionally, we see significant potential in other major segments including Drug Discovery and Regenerative Medicine where we feel our technology could truly have a paradigm shifting impact on these fields. |