Jeanne L. Becker

Jeanne L. Becker, Ph.D.

Jeanne L. Becker, Ph.D. is science advisor to Nano3D Biosciences. Dr. Becker was the founding President, CEO and Executive Director of the Center for the Advancement of Science in Space (CASIS), the management organization for the International Space Station (ISS) U.S. National Laboratory. Her previous posts include serving as Associate Director of the John M. Eisenberg Center for Clinical Decisions and Communications Science, a partner organization to the United States Agency for Healthcare Research and Quality; Vice President and Associate Director of the National Space Biomedical Research Institute, a partner organization to NASA; and Chair of the National Advisory Committee for the Women’s Health Research Coalition, a Washington DC-based network of leaders in academic medical, health and scientific institutions. Dr. Becker also served as Chief Science Officer for Astrogenetix, Inc., and was part of the research team using the conditions of microgravity to uncover novel targets for the development of bacterial vaccines and therapeutics. These pathfinder missions were designed by NASA as a national priority to validate the use of space for new biomedical discovery, and to demonstrate the value and importance of ISS as a research platform. The work resulted in the development of a novel in-flight method to assess host-pathogen interactions and microbial virulence in microgravity.

Dr. Becker has held faculty positions at Baylor College of Medicine and the University of South Florida College of Medicine, where her research focused on the development of three dimensional models of human breast and ovarian cancer, using the Rotating Wall Vessel developed by NASA. The three dimensional cellular constructs generated in these models reproduce many aspects of cancer, by creating tissue like architecture that exhibits rapid onset drug resistance as occurs in human disease. This work was selected as part of the suite of the first cell culture studies performed aboard the ISS, on Increment 3. In addition, she has developed a three dimensional cell culture paradigm based upon diamagnetically stabilized magnetic levitation, with two patents filed on this technology. Dr. Becker has had the opportunity to testify on several occasions before the United States Congress on her work and on the space program’s contributions to medical research, and is a recipient of NASA Space Life Sciences Directorate Professional Achievement Award.